Central nervous system (CNS) depressants.Melatonin might worsen blood pressure in people taking blood pressure medications. Melatonin might inhibit the effects of anticonvulsants and increase the frequency of seizures particularly in children with neurological disabilities. Combining use of melatonin with them might increase the risk of bleeding. These types of drugs, herbs and supplements reduce blood clotting. Anticoagulants and anti-platelet drugs, herbs and supplements.Talk to your child's doctor before giving melatonin to a child. However, good bedtime habits are usually recommended as an initial treatment. Small studies have suggested melatonin might help treat sleep disturbances in children with a number of disabilities. It's not clear whether melatonin can improve daytime sleep quality and duration in people whose jobs require them to work outside the traditional morning to evening schedule. Evidence shows that melatonin can improve jet lag symptoms, such as alertness and daytime sleepiness. Melatonin might be more beneficial for older adults who could be melatonin deficient. Research suggests that melatonin might slightly reduce the time it takes to fall asleep, but its effects on sleep quality and total sleep time aren't clear. Research shows that melatonin reduces the length of time needed to fall asleep and advances the start of sleep in adults and children with this condition. In this disorder, your sleep pattern is delayed two hours or more from a conventional sleep pattern, causing you to go to sleep later and wake up later.

Delayed sleep phase (delayed sleep-wake phase sleep disorder).Melatonin can help improve these disorders in adults and children. Circadian rhythm sleep disorders in the blind.Studies show that it may be effective at reducing heartburn and GERD symptoms when used alone or with medication.Research on melatonin use for specific conditions shows: Melatonin can block stomach acid secretion and nitric oxide synthesis. One study in 36 people showed that taking melatonin alone or with omeprazole - a common GERD medication - was effective at relieving heartburn and discomfort ( 6).Īnother study compared the effects of omeprazole and a dietary supplement containing melatonin along with several amino acids, vitamins and plant compounds in 351 people with GERD.Īfter 40 days of treatment, 100% of people taking the melatonin-containing supplement reported a reduction in symptoms compared to only 65.7% of the group taking omeprazole ( 20). It also decreases the production of nitric oxide, a compound that relaxes your lower esophageal sphincter, allowing stomach acid to enter your esophagus ( 20).įor this reason, some research suggests that melatonin may be used to treat heartburn and GERD. Melatonin has been shown to block the secretion of stomach acids. Gastroesophageal reflux disease (GERD) is a condition caused by the backflow of stomach acid into the esophagus, resulting in symptoms like heartburn, nausea and belching ( 19). One study found that melatonin capsules may help reduce symptoms, but other research is inconclusive. Seasonal depression may be related to changes in your body’s circadian rhythm. However, other research is still inconclusive on the effects of melatonin on seasonal depression.įor instance, another review of eight studies showed that melatonin was not effective at reducing symptoms of mood disorders, including bipolar disorder, depression and SAD ( 11).įurther research is needed to determine how melatonin may impact symptoms of seasonal depression. Some research indicates that it could be linked to changes in your circadian rhythm caused by seasonal light changes ( 10).īecause melatonin plays a role in regulating circadian rhythm, low doses are often used to decrease symptoms of seasonal depression.Īccording to one study in 68 people, alterations in circadian rhythm were shown to contribute to seasonal depression, but taking melatonin capsules daily was effective at reducing symptoms ( 5). This type of depression is related to changes in the seasons and occurs each year around the same time, with symptoms typically appearing in late fall to early winter. Seasonal affective disorder (SAD), also called seasonal depression, is a common condition that is estimated to affect up to 10% of the population worldwide ( 9).

Could Reduce Symptoms of Seasonal Depression

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